Ja’Marr Chase stands as the fulcrum of a bold, high-upside draft plan for 10-team, single-QB, PPR leagues. With Cincinnati keeping its offensive core intact, Chase’s top-3 floor and elite ceiling feel safe enough to lock him as the opening pick, while the blueprint stresses loading elite quarterback and tight end early to maximize weekly upside. The strategy then pivots to stacking running backs and wide receivers in the mid-to-late rounds, chasing high-upside darts at receiver and back half of the draft to balance risk and reward.

The guide traverses round-by-round targets, highlighting Chase, then naming top QB/TE pairs to secure in early picks before the slate tightens. It emphasizes sustained pass-friendly environments, injury risk considerations, and the importance of environment when projecting rookie or second-year talents. It also frames late-round lottery tickets—think explosive WRs and RBs with clear paths to volume—as essential ballast for a competitive roster in redraft, PPR settings.

Josh Jacobs lands at No. 33 in the NFL Top 100, signaling a blockbuster season ahead as a Green Bay back who excelled in 2024 with 1,329 rushing yards and 15 TDs across his first year in Green Bay. The Week 7 showdown against the Arizona Cardinals looms as a critical test for Green Bay’s ground game, with Jacobs facing a revamped front by a defensively-minded opponent. The NFL Top 100 rollouts also spotlight three Cardinals in the list—Budda Baker at No. 34, Trey McBride at No. 65, and Josh Sweat at No. 95—setting up intriguing cross-division matchups as the schedule unfolds. Cardinals opponents from the Top 100 include Tristan Wirfs, George Kittle, CJ Stroud, Puka Nacua and Bijan Robinson among others, painting a wide canvas for fantasy managers to chase value based on weekly adagios and matchup heat. State Farm Stadium hosts Week 7’s clash that could swing the Packers’ early-season momentum and offer Jacobs a notable fantasy ceiling against a Cardinals defense tinkering with its front seven.

Arizona Cardinals push to shore up interior line depth after Hayden Conner's preseason knee injury. They hosted tryouts for Brady Latham and Dohnovan West, signaling a plan to add guard- or center-depth before final cuts. A released receiver, Kelly Akharaiyi, opened a roster spot as the team evaluates options that can contribute in the barrage of August exhibitions.

Brady Latham, undrafted in 2024 from Arkansas, carries NFL stints with the Jets and Browns. Dohnovan West, a center from Arizona State and undrafted in 2022, spent time with the 49ers but didn’t stick. With Conner sidelined, the Cardinals pursue a reliable interior piece who can slot at guard or center, aiming to stabilize the line for the regular season and maintain roster flexibility through cuts.

CeeDee Lamb lands at No. 35 in the NFL Top 100 as the Cowboys meet the Cardinals in Week 9 on Monday Night Football. Lamb’s 2024 numbers—101 receptions for 1,194 yards and 6 TDs in 15 games—came with Dak Prescott missing nine games, underscoring Lamb’s elite volume even without a perfect QB. He’s 0-3 versus Arizona in his career, a narrative that adds pressure to Dallas’s passing attack on the road. The Cardinals’ list of top opponents this season features Lamb prominently, marking a flagship fantasy matchup in 2025.

Across the league’s Top 100 reveals, Arizona faces an array of star names and playmakers, highlighting a formidable slate for its defense and a prime chance for Lamb to push fantasy output. Week 9 on prime time should spotlight Lamb’s route-running and target share, with Prescott’s health and the Cards’ coverage being pivotal factors for fantasy managers.